Validation UV Spectrophotometric Method to Determine Entrapment Efficiency of Ocular Polymeric Nanoparticle Levofloxacin Hemihydrate
Penulis/Author
INDRI MAHARINI (1); Dr.rer.nat. Ronny Martien, M.Si. (2); Prof. Dr. apt. Akhmad Kharis Nugroho, S.Si., M.Si. (3); dr. Supanji, Sp.M(K), M.Kes., Ph.D. (4); Dr. Adhyatmika, M.Biotech., Apt. (5)
Tanggal/Date
31 2021
Kata Kunci/Keyword
Abstrak/Abstract
ABSTRACT:
Simple, easy, and economical UV spectrophotometric methods have been developed using simulated tear fluid (STF) solvent to determine levofloxacin hemihydrate (LEVH) levels in ocular nanoparticles, as indicated by the % entrapment efficiency. A maximum wavelength of levofloxacin at 288nm, with a 4.0-12.0μg/mL concentration, shows linear results with a correlation coefficient (r) of 0.9997 and an average % recovery of 99.920 –100.804%. The developed method is able to use for the analysis of levofloxacin hemihydrate in nanoparticle preparations.
Rumpun Ilmu
Farmasetika dan Teknologi Farmasi
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
74_RJPT_14_10_2021.pdf
[PAK] Full Dokumen
2
Turnitin RJPT Validation UV Spectrophotometric Method to Determine Entrapment Efficiency of Ocular Polymeric Nanoparticle Levofloxacin Hemihydrate.pdf
[PAK] Cek Similarity
3
12_ Surat Pernyataan UV Spectrophotometric- dr_ Supanji.pdf
Dokumen Pendukung Karya Ilmiah (Hibah, Publikasi, Penelitian, Pengabdian)
4
Validation UV Spectrophotometric Method to Determine Entrapment Efficiency of Ocular Polymeric Nanoparticle Levofloxacin Hemihydrate.pdf
