| Abstrak/Abstract |
Abstract: Relapse after orthodontic treatment occurs at a rate of about 70 to 90%, and this phenomenon
is an orthodontic issue that has not yet been resolved. Retention devices are one attempt at prevention,
but they require a considerable amount of time. Most orthodontists continue to find it challenging
to manage orthodontic relapse; therefore, additional research is required. In line with existing
knowledge regarding the biological basis of relapse, biomedical engineering approaches to relapse
regulation show promise. With so many possible uses in biomedical engineering, polymeric materials
have long been at the forefront of the materials world. Orthodontics is an emerging field, and
scientists are paying a great deal of attention to polymers because of their potential applications
in this area. In recent years, the controlled release of bisphosphonate risedronate using a topically
applied gelatin hydrogel has been demonstrated to be effective in reducing relapse. Simvastatin
encapsulation in exosomes generated from periodontal ligament stem cells can promote simvastatin
solubility and increase the inhibitory action of orthodontic relapse. Moreover, the local injection of
epigallocatechin gallate-modified gelatin suppresses osteoclastogenesis and could be developed as a
novel treatment method to modify tooth movement and inhibit orthodontic relapse. Furthermore,
the intrasulcular administration of hydrogel carbonated hydroxyapatite-incorporated advanced
platelet-rich fibrin has been shown to minimize orthodontic relapse. The objective of this review was
to provide an overview of the use of polymer materials to reduce post-orthodontic relapse. The most
promising polymeric materials and their potential orthodontic uses for the prevention of orthodontic
relapse are also discussed. |
