Karya
Judul/Title The Metastasis Behavior In The Cervical Cancer Mathematical Model
Penulis/Author TRI SRI NOOR ASIH (1) ; Prof. Dr. Fajar Adi Kusumo, S.Si., M.Si. (2); Dr.rer.nat. Lina Aryati, M.S. (3); dr. Mardiah Suci Hardianti, Ph.D. Sp.PD-KHOM (4)
Tanggal/Date 2015
Kata Kunci/Keyword
Abstrak/Abstract We consider the mathematical model which shows the dynamics of the cervical cancer cells based on the natural history of cervical cancer. The model has two equilibria, one is stable and the other is unstable which is saddle-type. In this paper, we show numerically that the stable manifold of this equilibrium separates two types of solution of the dynamical system. The first type is the solutions which tend to the stable equilibrium, and the second type is the solutions which is convergent to the unstable manifold of the equilibrium. The unstable manifold corresponds with medical interpretation as a threshold of metastasis condition. We also do simulation to show the movement of the separatrix related to the variation of the parameter value. The movement of the separatrix shows corresponds with the maximal progression rate from the precancerous to the cancerous stage. Increasing the maximal progression rate from precancerous to cancerous or decreasing the difference between precancerous ploriferation and apostosis rate will expand the domain of solutions that convergent to the stable equilibrium. These behaviors can be used as an alternative treatment for cervical cancer patient.
Rumpun Ilmu Matematika
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
1Jurnal Published 2015 (cover, editorial, daftar isi) The Metastasis Behavior In The Cervical Cancer.pdf[PAK] Halaman Cover
2Jurnal Published 2015 (artikel) The Metastasis Behavior in The Cervical.pdf[PAK] Full Dokumen
3The Metastasis Behavior In The Cervical Cancer Mathematical Model.pdf[PAK] Cek Similarity
42023 Maret 16 - dr MS - Surat Ket EC - The metastasis.pdfDokumen Pendukung Karya Ilmiah (Hibah, Publikasi, Penelitian, Pengabdian)