The effectiveness of topical vitamin D3 for dry skin in elderly
Penulis/Author
dr. He Yeon Asva Nafaisa, M.Sc., Sp.D.V. (1); dr. Fajar Waskito Sp.KK(K) M.Kes. (2); Dr.rer.nat. Ronny Martien, M.Si. (3); Prof. Dr. Med. dr. Retno Danarti, Sp.KK(K). (4)
Tanggal/Date
24 2024
Kata Kunci/Keyword
Abstrak/Abstract
Dry skin is one of the most common dermatoses found in the elderly. Vitamin D is an essential fat-soluble vitamin that has a role in repairing the skin barrier. Topical administration of vitamin D3 (VD3) is expected to increase skin hydration in the elderly. Thirty-two participants were divided into two groups, namely 5000 IU VD3 and the base lotion groups. The assessment was carried out by calculating the overall dry skin score (ODS), transepidermal water loss (TEWL), and skin capacitance every 4 weeks for 12 weeks. All groups showed an improvement in ODS, a decrease in TEWL, and an increase in skin capacitance value at the end of the measurement and no significant side effects reported. The 5000 IU VD3 lotion group had the highest level of skin hydration compared to the other group (p>0,05). We conclude that the administration of 5000 IU VD3 lotion may be administrated safely and improve skin hydration in the elderly but is not more effective than base lotion.
