Abstrak/Abstract |
Fine needle aspiration biopsy (FNAB) is a relatively non-invasive diagnosis of
musculoskeletal lesions that is very challenging in some musculoskeletal cases.
This study aimed to evaluate the diagnostic utility of FNAB in musculoskeletal
lesions. This was a retrospective cross-sectional study involving 180
musculoskeletal patients who underwent FNAB procedure, with or without
ultrasound-guided in the Department of Anatomical Pathology, Faculty of
Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito
General Hospital, Yogyakarta between 2018 and 2021. The obtained data were
then statistically analyzed for sensitivity, specificity, and accuracy. Of 180
cases, 90 (50%) were confirmed with histopathology examination. Further
analysis revealed that 33 cases were confirmed positive, 45 patients were
true negative, 2 cases were false positive, and 10 were cases false negative.
The overall diagnostic sensitivity, specificity, and accuracy of FNAB in
musculoskeletal lesions were 76.8, 95.7, and 83%, respectively. FNAB can lead to
misinterpretation in cases that show similar morphologic features. Therefore,
clinical information and imaging results are necessary to be correlated. In
conclusion, FNAB is an efficient and effective technique for early diagnosis
in musculoskeletal cases. FNAB can be used to establish the diagnosis of an
inoperable tumor because of its high accuracy |