Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from the Gandapura Oil
Penulis/Author
Dr. Muhammad Idham Darussalam Mardjan S.Si., M.Sc. (1); Dhina Fitriastuti (2); Prof. Drs. Bambang Purwono, M.Sc., Ph.D. (3); Prof. Drs. Jumina, Ph.D. (4)
Tanggal/Date
10 2019
Kata Kunci/Keyword
Abstrak/Abstract
This study describes a simple synthetic method to prepare 1-(2-methoxybenzyl)-1,10-
phenanthrolin-1-ium bromide from gandapura oil. The salt was synthesized in four steps.
Initially, commercial gandapura oil was directly subjected to the alkylation reaction under
basic condition using dimethyl sulfate to give methyl 2-methxybenzoate in 86% yield.
Next, the produced benzoate ester was reduced by LiAlH4 to produce 2-methoxybenzyl
alcohol in 67% yield. The treatment of benzyl alcohol with phosphorus tribromide under
solvent free condition produced the corresponding benzyl bromide (in 67% yield), which
was directly introduced into bimolecular nucleophilic substitution reaction with 1,10-
phenantroline monohydrate to finally give the desired product in 63% yield.
