| Penulis/Author |
RINA WIJAYANTI (1) ; Prof. Dr. apt. Subagus Wahyuono, M.Sc. (2); Prof. Dr. Ika Puspita Sari, S.Si., M.Si., Apt. (3); Prof. Dr. dr. Dicky Moch Rizal, M.Kes., Sp.And., AIFM. (4) |
| Abstrak/Abstract |
One of the health problems is infertility, with an incidence of 15-20%
of around 50 million couples, which men account for about 50% of all cases. Parijoto
fruit (Medinilla speciosa Blume) is empirically used to increase fertility. The purpose
of this study was to determine the stimulatory effect of methanol extract, insoluble
and soluble fraction of n-hexane parijoto on the quantity spermatozoa.
This study used 28 male SD rats, divided into VI groups, where group I was normal;
group II; III; IV; are methanol extract groups with doses 100 mg/kgBW; 250
mg/kgBW; and 500 mg/kgBW, group V is n-hexane insoluble fraction 500
mg/kgBW, and group VI is n-hexane soluble fraction 500 mg/kgBW, each given
orally for 14 days. The parameter observed was the quantity spermatozoa. The data
obtained were analyzed using Kruskal-Wallis, and Mann-Whitney.
The results showed the mean quantity spermatozoa in groups I, II, III, IV, V, and VI
were respectively 26.8±1.6; 27.1±1.3; 30.4±1.3; 43.5±1.3; 67.1±2.8; and 50.1±1.9
(million/ml ejaculate). There were significant differences between groups I and
groups IV, V and VI.
Methanol extract, insoluble and soluble fraction of n-hexane parijoto fruit were able
to provide a stimulating effect on the quantity spermatozoa in SD male rats.
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