| Abstrak/Abstract |
Insulin resistance is a risk factor for type 2 diabetes mellitus (T2DM) associated with waist circumference and body fat percentage. Nutritional therapy especially the consumption of dietary fiber has a beneficial effect to improve insulin sensitivity. The purpose of this study was to investigate the effect of high fiber snack in homeostatic model assessment of insulin resistance (HOMA-IR), waist circumference, and body fat percentage in T2DM patients.Total of 20 T2DM patients, age of 40-60 years recruited from the Policlinic of Endocrine, General Hospital Dr. Sardjito, Yogyakarta, Indonesia. The subjects received a 32g daily snacks made from a mixture of Dioscorea esculenta, arrowroot, cassava and pumpkin, for 4 weeks. The HOMA-IR index, waist circumference, and body fat percentage were measured twice (before and after intervention). Consuming a high fiber snacks for 4 weeks reduced the HOMA-IR index (p=0.010) and waist circumference (p=0.001) significantly. However, it did not change the percentage of body weight (p=0.138) in T2DM. Reduction of waist circumference has a positive correlation (p=0.369; r=-0.212) with reduction of HOMA-IR index.This study shows that consuming high-fiber snacks may improve insulin sensitvity and reduce waist circumference, but did not affect percentage of body fats. |
