Regulatory Elements of stx2 Gene and The Expression Level of Shiga-Like Toxin 2 in Escherichia coli O157:H7
Penulis/Author
I Wayan Suardana (1); Komang Januartha Putra Pinatih (2); drh. Dyah Ayu Widiasih, Ph.D. (3); Prof. Dr. drh. Wayan Tunas Artama (4); Prof. Dr. Budi S. Daryono, M.Agr.Sc. (5); Widya Asmara (6)
Tanggal/Date
2018
Kata Kunci/Keyword
Abstrak/Abstract
Shiga-like toxin (Stx) is an important factor in the pathogenesis of Escherichia coli O157:H7 infection and is responsible for some severe complications. Stx2 is usually associated with hemolytic uremic syndrome in humans. Its expression is regulated by elements located upstream of the stx2 gene, including stx2-promoter sequence, ribosome binding site, and the antiterminator q gene. The present study aimed to find the correlation between regulatory elements and the expression level of Stx2 in two local isolates of E. coli O157:H7.
