Karya
Judul/Title Rationality of Antiretroviral Therapy for HIV/AIDS inpatients in a Hospital in Yogyakarta
Penulis/Author Dr. apt. Nanang Munif Yasin, S.Si., M.Pharm. (1)
Tanggal/Date 2008
Kata Kunci/Keyword
Abstrak/Abstract The monitoring result at 25 referral hospitals for HIV/AIDS patients is still found obstacles in the antiretroviral (ARV) using. The aims of this study are to know the pattern of antiretroviral using according to the characteristic of HIV/AIDS patients and to evaluate the rational therapy based on the National Guidance of Antiretroviral Therapy from Departemen Kesehatan Republic of Indonesia in 2004. Non-experimental study with descriptive evaluative analytical approach was used as design of this study. Data was collected retrospectively from 32 HIV/AIDS patients as sample of the study. The inclusion criteria are complete identity in medical record to get information about theirs characteristic, HIV/AIDS diagnose and antiretroviral therapy during inpatients care in a hospital in Yogyakarta for the period 2004-2005. The characteristic of patients shows the comparison between male and female patients in ratio 31:1, most of them are 20-29 years old (65,6%). It also shows the highest risk of the Injecting Drug User (IDU) group (65,6%). The study found that the first choice regimen which is applied most often is combination of zidovudine+lamivudine+nevirapine (50%). All patient get precisely dosage of ARV according to the recommendation of Depkes R.I (2004), but there is various frequency once daily in use efavirenz and twice daily in ARV besides efavirenz. The rational therapy analysis found that 100% of 13 patients get precisely indication, 65,6% of 32 patients get precisely drug of choice, 62,5% of 32 patients get precisely dosage, and 80% of 10 patients get precisely monitoring.
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