Quantitative analysis of lard in cosmetic lotion formulation using FTIR spectroscopy and PLS calibration
Penulis/Author
Prof. Dr.rer.nat. apt. Raden Rara Endang Lukitaningsih, S.Si., M.Si. (1); apt. Miftahus Sa'adah, S.Farm., M.Si. (2); Purwanto, M.Sc., Ph.D., Apt. (3); Prof. Dr. Abdul Rohman, S.F., M.Si., Apt. (4)
Tanggal/Date
2012
Kata Kunci/Keyword
Abstrak/Abstract
Fourier transform infrared (FTIR) spectroscopy
in combination with chemometrics of partial least squares
(PLS) has been optimized for rapid determination of lard in
a binary mixture with palm oil in a cosmetic lotion formulation. Lard, palm oil, and a binary mixture were
extracted from matrix samples using liquid–liquid extraction, evaporated with a vacuum rotary evaporator, and the
fat/oil yielded was further subjected to FTIR spectrometric
measurement using attenuated total reflectance (ATR) as a
sampling handling technique. The level of lard in the
mixture with palm oil in the lotion formulation was
quantified at frequency region of 1,200–1,000 cm
-1
. The
PLS calibration model reveals good correlation between
the actual value of lard (x-axis) and the FTIR predicted
value (y-axis) with a coefficient of determination (R
2
)of
[0.99. Furthermore, the classification between lotions with
and without lard in their formulation was performed using
principal component analysis using the same frequency
region used for quantification. The developed method was
subsequently used for analysis of cosmetic lotions commercially available in the market. All samples analyzed did
not contain lard in their formulations
Rumpun Ilmu
Analisis Farmasi dan Kimia Medisinal
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
Lukitaningsih 2012, Quantitative analysis of lard.pdf
