Karya
Judul/Title Potency of Lactobacillus plantarum Dad-13 and Sweet Potato (Ipomoea batatas) Fiber as Immunomodulator in Rats Infected with Salmonella typhimurium
Penulis/Author Prof. Dr. Ir. Nurliyani, M.S., IPM (1) ; Prof. dr. Madarina Julia, Sp.A(K), MPH., Ph.D. (2); Prof. Dr. Ir. Eni Harmayani, M.Sc. (3); Dr. apt. Muthi' Ikawati, M.Sc. (4); Prof. Dr. Ir. Endang Baliarti, SU. (5)
Tanggal/Date 2015
Kata Kunci/Keyword
Abstrak/Abstract Lactobacillus plantarum Dad-13 that isolated from “dadih” (traditional Indonesian fermented milk) has been known as probiotic, while sweet potato fiber has been proven as an effective prebiotic. The objective of this study was to evaluate the potency of Lactobacillus plantarum Dad-13 and sweet potato fiber as immunomodulators in terms of intestinal secretory immunoglobulin A (sIgA) and splenocyte gamma-interferon (IFN-?). Sixty male Sprague Dawley rats (uninfected and infected) were divided into five groups: AIN-93, Indonesian children diet (ICD), Sweet potato fiber (SPF), SPF + Lactobacillus plantarumDad-13 (SPFL), and fructooligosaccharides + Lacto-B (FOSL). After diet intervention, the rats were killed and sampled including intestinal fluid, spleen and caecal digesta. The results showed that soluble fiber such as sweet potato fiber could not increase the number of lactobacilli in infected rats, but could play a role in mucosal immune response through the increasing of sIgA. While, Lactobacillus plantarum Dad-13 contained in the combination with sweet potato fiber may has potency in systemic immune stimulation, because of the tendency to increase level of splenocyte IFN-?in infected rats.
Rumpun Ilmu Teknologi Pangan dan Gizi
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
144964-154982-3-PB.pdf
22015-Nurliyani et al.pdf[PAK] Full Dokumen
3J of Food Research Editorial Board.pdf[PAK] Halaman Editorial
4J of Food Research 4(3) 2015 Cover.pdf[PAK] Halaman Cover
5J of Food Research 4(3) 2015 Table of content.pdf[PAK] Daftar Isi
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