Karya
Judul/Title POTENCY OF BELIMBING WULUH (AVERRHOA BILIMBI) AS ANTIOXIDANT AND TYROSINASE INHIBITOR FOR SKIN WHITENING PRODUCTS
Penulis/Author Prof. Dr.rer.nat. apt. Raden Rara Endang Lukitaningsih, S.Si., M.Si. (3)
Tanggal/Date 2019
Kata Kunci/Keyword
Abstrak/Abstract Hyperpigmentation is one of the skin damage characterized by the appearance of dark spots on the skin. The appearance of dark spots on the skin is caused by the increase of melanin substances. Melanin substances do have a role in the color of a person's skin pigments as excessive production of melanin will cause dark spots on the skin. Various causes are considered to be the trigger for the appearance of spots on the skin. One of them, hyperpigmentation occurs because of exposure to UV rays from the sun [1]. Melanin is formed through a pathway called melanogenesis with the help of the tyrosinase enzyme. This formation is affected by exposure to UV light with the mechanism of melanocyte proliferation. Hyperpoliferation of melanocytes results in over production of melanin which can cause hyperpigmentation of the skin which causes black spots and potentially melanoma [2]. This makes the prevention important to do one of them by controlling the enzyme tyrosinase. One of Indonesia's tropical country plants is belimbing wuluh. Belimbing wuluh (Averrhoa bilimbi) is known to contain efficacious compounds such as phenolics such as flavonoids [3]. Belimbing wuluh fruits contains total phenol compounds of 65 mg GAE/g extract. Phenolic compounds and flavonoids have activities as antioxidants [4, 5]. The bond of flavonoids with copper and their antioxidant effects have been reported to play a role in inhibiting the action of the enzyme tyrosinase [6]. Never reported about antioxidant activity and inhibitory activity of tyrosinase belimbing wuluh leaves and fruits. The purpose of this study was to know the potential of belimbing wuluh as an antioxidant and tyrosinase inhibitor in different parts.
Rumpun Ilmu Analisis Farmasi dan Kimia Medisinal
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
1Naskah Jurnal of Pharma Research, 8 issue 4 2019.pdf[PAK] Full Dokumen
2Editorial Board.pdf[PAK] Halaman Editorial
3Table of Content.pdf[PAK] Daftar Isi
434_ Turnitine Naskah Jurnal of Pharma Research, Blimbing, 8 issue 4 2019.pdf[PAK] Cek Similarity