Physicochemical properties and antibacterial studies of hydroxyapatite scaffold extracted from indonesian limestone
Penulis/Author
Dr. Juliasih Partini, S.Si., M.Si. (1); SILMA MAULA BILQIS (2); FIKRI ADDIN SALIMY (3); Ihwanul Aziz (4); Dr. Mona Sari, S.Si., M.Sc. (5); Nilam Cahyati (6); Prof. Dr. Eng. Yusril Yusuf, S.Si., M.Si., M.Eng. (7)
Tanggal/Date
31 2024
Kata Kunci/Keyword
Abstrak/Abstract
This research successfully fabricated scaffolds with hydroxyapatite (HA) from limestone and with HA coating using the gas
foaming method. HA coating uses the addition of cinnamon oil in HA from limestone and impacts the scaffold’s antibacterial
properties. Scaffold fabrication uses the gas foaming method with a drying time of 30 minutes and 0.9 grams of HA. The
fabricated scaffold is then characterized using an X-ray diffractometer (XRD), Fourier Transform Infra-Red (FTIR), and
Scanning Electron Microscopy (SEM). Then, the antibacterial analysis of scaffolds using the diffusion method. Scaffolds from
HA coating have smaller crystal sizes, fewer agglomerations, smaller particle sizes, and a more even distribution and size of
pores. Scaffolds with HA coating have higher porosity than scaffolds with HA only. HA coating shows that adding cinnamon
oil as an antibacterial agent can inhibit strong bacteria for S. aureus bacteria with an inhibition zone size of 11 mm.
