| Abstrak/Abstract |
As one of the essential materials in dentistry, mineral trioxide aggregate (MTA) has been extensively used for root
fracture repair, apexification, and root filling material due to its good sealing ability and biocompatibility.
However, poor mechanical properties and low antibacterial efficacy are significant limitations of MTA for
medical applications. To overcome these problems, we modified MTA by incorporating ZnO and chitosan in this
study. The modification was performed by adding ZnO in various concentrations (5, 10, and 15 wt%) while
preparing MTA and 4% chitosan solution as the hydration liquid. The modified-MTA samples were characterized
with TG/DTA, XRD, FTIR, and SEM instrumentations. The effects of ZnO and chitosan on mechanical strength,
radiopacity, pH, Ca
ions release, and antibacterial properties of MTA samples were evaluated. It
found that the modified MTA altered to a more compact structure and ultimately influenced the properties of
hydrated products. The modified MTA’s radiopacity and weight loss measurements complied with ISO standards
as endodontic materials. Antibacterial evaluation against Enterococcus faecalis and Pseudomonas aeruginosa
demonstrated enhanced efficacy due to the synergistic effect of ZnO and chitosan in MTA. Incorporating 10 wt%
ZnO and 4% chitosan solution into the synthesized MTA was the optimum composition, significantly improving
the mechanical and antibacterial properties. All the demonstrated tests revealed the potential of the modified
MTA as a promising candidate for dental restorative material. |
