Abstrak/Abstract |
Vaccination is the one method to control disease of Motile Aeromonas septicemia on African catfish (Clarias gariepinus). The aim of this research was to determine the effect of booster intervals using Aeromonas hydrophila debris on immune response of African catfish. The research was contructed as CRD, c.i. 95 %. Firstly, thirty five catfish were reinfected and reisolated (three times) with A. hydrophila. The virulent A. hydrophila was broken by sonication into debris. Thirty catfish were divided into six treated groups, i.e (1) control (K1), (2) placebo control (K2) with debris vaccination, (3) without booster (P1), (4) once booster (P2), (5) twice boosters (P3), (6) three times boosters (P4). Booster interval was once a week. Data were taken for ten weeks. The parameter assessed was antibody titer were analyzed by ANOVA and Ducan's multiple Range Test. The research showed that the highest antibody titer was reached on the 2-3 week, and significan differences among all treatments and controls. The vaccination could increase the adaptive response immunity through the increase the adaptive response immunity through the increase the adaptive response immunity through the increase of antibvody titer. Debris vaccine with three times boosters (P4) was the most effective vaccination |