Karya
Judul/Title On Arrival High Blood Glucose Level is Associated With Detrimental and Fatal Hospitalization Outcomes for Acute Coronary Syndrome
Penulis/Author dr. Anggoro Budi Hartopo, Sp.PD., M.Sc., Sp.JP., Ph.D (1); Prof. Dr. dr. Budi Yuli Setianto, Sp.PD-KKV., Sp.JP(K) (2); Dr. Med. dr. Putrika Prastuti Ratna Gharini, Sp.JP(K) (3); Prof. Dr. dr. Lucia Kris Dinarti, Sp.PD., Sp.JP(K). (4)
Tanggal/Date 2011
Kata Kunci/Keyword
Abstrak/Abstract Background: High blood glucose level is frequently encountered in acute coronary syndrome. We investigated the effects of high blood glucose measured on arrival on hospitalization adverse events in acute coronary syndrome. Our study patients were Java- nese in ethnicity, which constitute half of population in Indonesia. We hypothesized that elevated blood glucose has detrimental ef- fects on hospitalization for acute coronary syndrome. Methods: We designed an observational cohort study and recruited 148 consecutive patients with acute coronary syndrome. Venous blood was collected on hospital arrival. High blood glucose level was determined as plasma glucose > 140 mg/dL. Adverse hospitalization events were recorded, i.e. mortality, acute heart failure, cardiogenic shock and heart rhythm disorders. Echocardiography examination was performed to determine left ventricular function. Results: The prevalence of on arrival high blood glucose among Javanese patients with acute coronary syndrome was considerably high (36%). On arrival high blood glucose was associated with acute heart failure (P < 0.001) and shock cardiogenic (P = 0.02). Heart rhythm disorders were higher in high blood glucose patients (P = 0.004). Left ventricular dysfunction was more prevalent in high blood glucose patients (P = 0.001) and ejection fraction was lower (P = 0.001). On arrival high blood glucose was independently associated with hospitalization adverse events (adjusted odds ratio = 2.3, 95% confidence interval: 1.1-4.9, P = 0.03) and hospital mor- tality (adjusted odds ratio = 6.9, 95% confidence interval: 1.2-38.6, P = 0.03). Conclusions: Our study suggests that on arrival high blood glu- cose among Javanese patients with acute coronary syndrome is considerably high and is associated with detrimental and fatal hos- pitalization outcomes.
Rumpun Ilmu Penyakit Jantung
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
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