Karya
Judul/Title New Report: Genome Mining Untaps the Antibiotics Biosynthetic Gene Cluster of Pseudoalteromonas xiamenensis STKMTI.2 from a Mangrove Soil Sediment
Penulis/Author DESY PUTRI HANDAYANI (1); Prof. Dr. Ir. Alim Isnansetyo, M.Sc. (2) ; Indah Istiqomah, S.Pi., M.Si., Ph.D (3); Prof. Dr. Jumina (4)
Tanggal/Date 2022
Kata Kunci/Keyword
Abstrak/Abstract Pseudoalteromonas is a genus of the marine Gammaproteobacteria that has many benefits for human life. The marine bacterium Pseudoalteromonas xiamenensis STKMTI.2 was isolated from a mangrove soil sediment in Setokok Island, Batam, Indonesia. The genome of this bacteria consists of 4,563,326 bp (GC content: 43.2%) with 1 chromosome, 2 circular plasmids, 2 linear plasmids, 4,824 protein-coding sequences, 25 rRNAs, 104 tRNAs, 4 ncRNAs, and 1 clustered regularly interspaced short palindromic repeats (CRISPR). The studied bacterium possessed cluster genes responsible for producing brominated marine pyrroles/phenols (bmp), namely, bmp8 and bmp9. Other gene clusters responsible for the synthesis of secondary metabolites were identified by using the anti-SMASH server, which returned five results, namely, non-ribosomal peptides, polyketide-like butyrolactone, Lant class I, and RiPP-like detected in chromosome 1, whereas prodigiosin was detected in plasmid unnamed 5. It suggesting that these whole-genome data will be remarkably important for the improved understanding of the biosynthesis of industrially important bioactive and antibacterial compounds produced by P. xiamenensis STKMTI.2.
Rumpun Ilmu Bioteknologi Perikanan
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
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