Measurement of Health Related Quality of Life in Malaria Patients in Indonesia using EQ-5D-5L
Penulis/Author
DIAN AMALIA MAKATITA (1); RESTU NUR HASANAH H (2); Dr. apt. Dwi Endarti, S.F., M.Sc. (3); Prof. Dr. Chairun Wiedyaningsih, M.Kes., M. App.Sc., .Apt. (4); Prof. Dr. Tri Murti Andayani, Sp.FRS., Apt. (5)
Tanggal/Date
2019
Kata Kunci/Keyword
Abstrak/Abstract
Introduction: Indonesia is one of the countries with high malaria
cases. In 2017 there were at least 261,167 malaria cases
nationally. West Papua is included in the 3 major provinces with
the highest incidence of malaria. Malaria disease alters patient’s
Quality of Life (QoL). Thus, measurement of Health Related
Quality of Life (HRQOL) is gaining importance.
Aim: This study was aimed at measuring HRQOL in malaria
patients and examining the relationship between sociodemographics and HRQOL.
Materials and Methods: Data were collected from 110 patients
with malaria visiting primary healthcare centres. It was a crosssectional study conducted from October to December 2018.
Measurement of HRQOL was done using the European Quality
of Life-Five Dimension-Five Level (EQ-5D-5L) instrument.
Descriptive analysis was used to analyse patients HRQOL in
terms of EQ-5D-5L descriptive system, EQ-5D-5L index scores
(utility), and European Quality-Visual Analog Scale (EQ-VAS).
Relationships between socio-demographics and HRQOL were
examined using multivariate regression analyses.
Results: Almost all of the respondents reported problems in
all domains. There were no responses of “extreme problems”
for any of the domains. “Pain/discomfort” (99%) and “usual
activities” (95.4%) domains were the most reported problems
among malaria patients. The mean EQ-5D-5L and VAS score
was 0.490±0.470 and 50.9±0.5, respectively. Utility score in
patients with severe malaria (0.349) was lower compared to
patients with mild malaria (0.571). Patients with health insurance
had a better QoL. Sociodemographic factors, particularly the
type (severity) of malaria and health insurance, contributed
36.9% to the HRQOL.
Conclusion: Malaria was associated with poor HRQOL and
particularly affected “Pain/discomfort” and “usual activities”
domains.
Rumpun Ilmu
Farmasi Umum dan Apoteker
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
Measurement of Health Related Quality of Life in Malaria Patients in Indonesia using EQ-5D-5L.pdf