| Penulis/Author |
RINA WIJAYANTI (1) ; Prof. Dr. apt. Subagus Wahyuono, M.Sc. (2); Prof. Dr. Ika Puspita Sari, S.Si., M.Si., Apt. (3); Prof. Dr. dr. Dicky Moch Rizal, M.Kes., Sp.And., AIFM. (4) |
| Abstrak/Abstract |
Parijoto fruit (Medinilla speciosa Blume) of Family Melastomataceae is a plants grow on the slopes of the Muria
Mountains, Colo Village, Kudus District, Indonesia. The methanol extract of Parijoto fruit was able to reduce
blood sugar levels, improve sexual function, exhibit moderate cytotoxicity in T47D cancer cells, potential for
chemoprevention, ability to lower glucose levels, antihyperlipidemic, antiobesity, stimulating effect on the
quantity spermatozoa, increase the number of Leydig cells, Sertoli cells, primary spermatocytes and
seminiferous tubule diameter. Parijoto fruit contains flavonoid compounds, saponins, terpenoids, glycosides and
tannins, beta-carotene and antioxidants, and alkaloids. So that these plants can be developed and preserved, it is
necessary to carry out continuous research, so that the types of compounds can be known. To determine the
content of active compounds from plants, and identification, so that pure compounds are obtained. This study
aims to provide information on the results of the isolation and identification of phytoconstituents from the
methanol extract of parijoto fruit. The methanol extract of parijoto fruit was diffracted using n-hexane. Fraction
then was continued with the isolation process. The process of isolation and identification of methanol extract of
parijoto fruit using Preparative Thin Layer Chromatography method. Structure these compounds were
determined based on the Gas chromatography-mass spectrometry (GC-MS), Fourier Transform Infrared
Spectroscopy (FT-IR) and NMR spectra. This study succeeded in isolating three compounds from the methanol
extract of parijoto fruit. Namely stigmasterol (1) of n-hexane fraction, stigmasterol (2) and 1-hexanol (3) of
methanol fraction.
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