Indole macrocycles formed by diindolylmethane ring closure
Penulis/Author
Prof. Drs. Bambang Purwono, M.Sc., Ph.D. (1); Naresh Kumar (2); David StC. Black (3)
Tanggal/Date
18 2022
Kata Kunci/Keyword
Abstrak/Abstract
Indole containing macrocyclic compounds can be formed from suitable diindolyl diesters and diamides by acidcatalysed reaction with formaldehyde to generate a 2,2′-linkage in the ring closure step. The alternative protocol in which macrocyclisation is attempted by lactone or lactam formation from starting 2,2′- diindolylmethane systems was unsuccessful in our examples.
