| Penulis/Author |
Prof. Dr. Dra. Sunarti, M.Kes. (1) ; Prof. Dr. Ir. Umar Santoso, M.Sc. (2); Dianandha Septiana Rubi, S.Gz., M.Sc. (3); Abrory Agus Cahya Pramana, S.Si., M.Sc. (4); Dr. dr. Emy Huriyati, M.Kes. (5); NADIA YASMINE (6) |
| Abstrak/Abstract |
Background: Dietary fiber decreases the glycaemic index and produces short-chain fatty acids (SCFAs) that will affect gastrointestinal hormones’s secretion. Glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) are intestinal satiety hormone signals, while ghrelin is a gastric appetite stimulator. Objective: This study investigated the effects of high-fiber snack, as tested snack, on glycaemic index, GLP-1, PYY and ghrelin secretions. Methods: The study involved ten participants who received both 42 g of tested snack and glucose solution as a standard by washout period for a week. The standard glucose was prepared by dissolving 50 g of glucose powder in 200 mL of water containing 200 Kcal, while 42 g of snack containing 195.8 Kcal and 11.70% fiber and 3132 ug?ta carotenes from arrowroot, pumpkin, sweet potato, and cassava. The blood samples were collected at 0 (after fasting 8-10 hours overnight), 30, 60, 90, and 120 minutes after consuming snack or standard glucose, and were used to determine the glycaemic index, insulin, PYY, ghrelin, and GLP-1 levels. Results: The glycaemic index of the tested snack is 69.14 that categorized as medium. The area under glucose curve of the tested snack was lower compared to standard glucose (p= <0.001), and the plasma glucose was lower than standard glucose. Compared to standard glucose, the tested snacks had the area under insulin curve lower than standard glucose, but it was not statistically significant (p= 0.082). No statistically significant also found in the GLP-1, PYY and ghrelin concentrations between both standard glucose and tested snack intervention (p= 0.948). Conclusion: Our results suggests that consuming high-fiber snacks, with medium glycemic index, may have no effect on GLP-1, PYY, and ghrelin, otherwise it could improve glucose and insulin homeostasis.
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