Identification of galactogogues in Gliricidia maculata
Penulis/Author
Ir. Sulvia Dwi Astuti SW, S.Pt., M.Sc., IPM (1); Prof. Dr. Ir. Budi Prasetyo Widyobroto, DESS., DEA., IPU., ASEAN Eng. (2); Prof. Dr. Ir. Ali Agus, DAA., DEA., IPU., ASEAN Eng. (3); Prof. Dr. Ir. Lies Mira Yusiati, SU., IPU., ASEAN Eng (4)
Tanggal/Date
6 2019
Kata Kunci/Keyword
Abstrak/Abstract
Galactogogues are substances used by periparturient dairy cows for boosting milk
production and preventing negative energy balance. A long-term use of commercial
galactogogues has a toxic effect to normal health status of both human and animals. The study
was conducted to identify herbal galactogogues from bioactive compounds of Gliricidia
maculata ethanol extract. The samples were harvested randomly from edible portion of plants
at optimal age (80 days). Lyophilization was carried out at 55°C for 3 days followed with
pulverization. The bioactive compounds were extracted using ultrasonic assisted extraction
method and identified by the GCMS-QP2010S SHIMADZU instrument with Rtx 5 MS
column. Spectra produced by MS was translated into chemical structures and data were
presented in form of retention time (minutes), peak area (%), molecular formula (CxHyOz),
molecular weight and the name of bioactive compound based on the similarity index of the
GCMS library. As the result, there were five major galactogogues of Gliricidia maculate
namelyphytol, 1-Octadecyne, 2,6,10,15,19,23-hexamethyl-Squalene, n-Eicosane and 4-
Hexadecen-6-yne which identified in this study. Since this study was the first work reporting
galactogogues derived from Gliricidia maculate, therefore application of its potential could be
implemented in the future study of dairy cattle feeding practices.
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
Sulvia Dwi Astuti et al_2019_Identification of galactogogues_IOP Conf_ Series Earth and Environmental Science 387 (2019) 012119.pdf
[PAK] Full Dokumen
2
Cek Similarity_Sulvia Dwi Astuti et al_2019_Identification of galactogogues_IOP Conf Series Earth and Environmental Science 387 (2019) 012119.pdf