Prof. Dr. Tri Murti Andayani, Sp.FRS., Apt. (1); Prof. Dr. Susi Ari Kristina, S.Farm., M.Kes., Apt. (2); Dr. apt. Dwi Endarti, S.F., M.Sc. (3); SEPTIANA TRI WAHYUNI (4); ANINDYA RAHMAWATI (5)
Tanggal/Date
4 2020
Kata Kunci/Keyword
Abstrak/Abstract
Cost-utility analysis requires data of severity-based health utility score for calculating the Quality adjusted life years. This study aims to figure out utility scores based on complications,
comorbidities and diabetes treatments in patients with type 2 diabetes mellitus.
The study was conducted using cross-sectional design in patients with type 2 diabetes mellitus who visited regional hospitals in Yogyakarta, Indonesia. Utility score was measured using EQ-5D-
5L questionnaire. The scoring was performed using a value set developed for the Indonesian population.
The results of the study in 418 patients with diabetes mellitus with an average age of 60.74 (SD=8.61) years showed that the utility score and the average Visual analog scale (VAS) value
were 0.74 (SD=0.22) and 74.60 (SD=12.23) respectively. Problems related to the mobility were reported in 42.67% of the patients, while for self-care domain in 11% , daily activity in 48% ,
pain/uncomfortable in 76.33%, and anxiety/depression in 44.33%. There were significant differences in the utility score based on complications related to DM, that the mean utility score of DM patients without complications was 0.79 (SD=0.16), with microvascular complications was 0.76 (SD=0.19), with macrovascular complications was 0.71 (SD=0.19) and with microvascular and macrovascular complications was 0.59 (SD=0.31). The lowest utility score was in the patients with stroke complications by 0.43 (SD=0.32). The differences in the therapeutic regimens given also indicated the different utility scores. Diabetes mellitus patients with complications showed lower utility scores. Health utility scores based on complications could be used as a supporting data in the pharmacoeconomic analysis.
Rumpun Ilmu
Farmasi Umum dan Apoteker
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
PSA_Tri Murti 2020.pdf
[PAK] Full Dokumen
2
Health utility score in type 2 diabetes mellitus.pdf
