| Abstrak/Abstract |
Whitening cosmetics with anti-melanogenesis activity are widely
popular globally. Numerous studies are underway to identify new ingredients
exhibiting anti-melanogenesis effects for the development of novel products.
There has been a notable surge in the utilization of natural anti-
hyperpigmentation agents sourced from marine origins for both
pharmaceutical and cosmetic applications. This review aims to provide an
overview of the antioxidant and anti-melanogenesis effect of brown seaweed
which harbors a significant quantity of fucoxanthin, serving as a skin
whitening agent. Secondary metabolites derived from brown algae have also
been harnessed for use in cosmetics. However, many of the reviewed articles
lack comprehensive investigations into molecular targets, essential for
fulfilling the criteria of cosmetic and pharmaceutical utilization. Recently,
various secondary metabolites, particularly carotenoids like fucoxanthin,
have been identified from brown seaweed, demonstrating anti-melanogenesis
properties and underlying mechanisms. Nevertheless, in vivo and clinical
investigations of marine algae-derived whitening agents remain scarce. The
novelty of this review lies in the discourse surrounding fucoxanthin as a major
carotenoid in brown algae, highlighting its antioxidant and anti-
melanogenesis potential. An anti-melanogenesis test is generally preceded by
an antioxidant activity test. Almost all brown algae exhibit notable
antioxidant effect compared to control, suggesting inherent antioxidant
properties. In addition, the melanogenesis effect of brown algae surpasses
that of controls. In the future, fucoxanthin compounds hold promise for
incorporation into cosmetics within the pharmaceutical industry. |
