Karya
Judul/Title External Quality Control for Dried Blood Spot-Based C-Reactive Protein Assay: Experience from the Indonesia Family Life Survey and the Longitudinal Aging Study in India
Penulis/Author Peifeng Hu (1) ; dr. Elizabeth Henny Herningtyas, M.Si., Ph.D. SpPK(K) (2); Varsha Kale (3); Eileen Crimmins (4); Arun R. Risbud (5); Heather McCreath (6); Jinkook Lee (7); John Strauss (8); Jennifer C. O/Brien (9); David E. Bloom (10); Teresa Seeman (11)
Tanggal/Date 16 2015
Kata Kunci/Keyword
Abstrak/Abstract Measurement of C-reactive protein (CRP), a marker of inflammation, in dried blood spots has been increasingly incorporated into community-based social surveys internationally. Although the dried blood spot-based CRP assay protocol has been validated in the United States, it remains unclear whether laboratories in other less-developed countries can generate CRP results of similar quality. We therefore conducted external quality monitoring for dried blood spot-based CRP measurement for the Indonesia Family Life Survey and the Longitudinal Aging Study in India. Our results show that dried blood spot-based CRP results in these two countries have excellent and consistent correlations with serum-based values and dried blood spot-based results from the reference laboratory in the United States. Even though the results from duplicate samples may have fluctuations in absolute values over time, the relative order of C-reactive protein levels remains similar, and the estimates are reasonably precise for population-based studies that investigate the association between socioeconomic factors and health.
Rumpun Ilmu Patologi Klinik
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
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