| Penulis/Author |
Dr. Toto Sudargo, SKM., M.Kes. (1); Dr. Rio Jati Kusuma, S.Gz., MS. (2); Tony Arjuna, S.Gz., M.Nut.Diet., AN., APD., Ph.D. (3); Dianandha Septiana Rubi, S.Gz., M.Sc. (5); Prof. Dr. Abdul Rohman, S.F., M.Si., Apt. (6); Rasita Amelia Hasnawati (7) |
| Abstrak/Abstract |
Abstract:In Indonesia, the prevalence of iron deficiency anemia is still high. Iron fortification in food usingsodium ferry EDTA (NaFeEDTA) potentially reduce the incidence of iron deficiency anemia. Iron deficient anemia was induced in female Wistar rats by feeding low iron (Fe) diet and was randomly divided into ten groups where one group was fed normal diet which serves as control group. Every treatment group willreceive Fe SO4, tempe and iron-fortified tempe (temFe) with iron dosage of 6, 12 and 24 ppm respectively for17days. Blood was drawn for serum iron (SI) and serum ferritin (SF) measurement. After treatment, temFe24ppm grouphas the highest SI and the highest SI changed compared with other treatment groupsalthoughno significant different (p>0.05) was observed between temFe 24 ppm group and FeSO424 ppmgroup for SI (139.36±1.58vs 134.10±2.73 ?g/dL) and SI changed (89.40±2.78 vs 84.47±2.41 ?g/dL). SF wasincreasedin all treatment diet with the highest was found in FeSO424 ppm group (73.25±3.16 ng/mL).However,SF level wasn’t significantly different between the FeSO424 ppm, tempe 24 ppm and temFe24ppmandgroup (p>0.05). Iron fortification in tempe with NaFeEDTA will restore both SI and SF in irondeficiency anemia. |
