| Abstrak/Abstract |
Background and aims: High levels of non-HDL and atherogenic cholesterol can induce
inflammation, and as risk factor for cardiovascular diseases. This study was to evaluate
the effects of fiber-rich snacks on non-HDL cholesterol, atherogenic index, and Creactive
protein (CRP) levels in type 2 diabetes patients (T2DM). Material and Methods:
Twenty T2DM patients, were recruited from the Policlinic of Endocrine, Dr. Sardjito
General Hospital, Yogyakarta, Indonesia. The subjects received daily 32g fiber-rich
snacks made of Dioscorea esculenta, arrowroot, cassava and pumpkin for 4 weeks.
Fasting non-HDL cholesterol, atherogenic index, CRP and HbA1c levels were measured
before and after intervention. Paired t-test was used to evaluate the results. Results: The
fiber-rich snack intervention in T2DM patients significantly reduced levels of non-HDL
cholesterol and CRP levels (p<0.05), but the decreased the atherogenic index was not
significant (p>0.05). The intervention also significantly reduced the CRP levels (p<0.05)
but did not affect HbA1c levels. Body weight, body mass index (BMI), waist
circumference decreased significantly after consuming the snacks (p<0.05). Conclusions:
This study showed fiber-rich snack has a positive effect in improving non-HDL
cholesterol, atherogenic index and CRP levels but does not affect HbA1c levels in T2DM
patients. |
