Effect of dentifrice containing crab-shell chitosan on the accumulation of dental plaque in fixed orthodontic appliances patients: a randomized controlled trial
Penulis/Author
drg. Josephine C Paula Heryumani Sulandjari, M.S., Sp.Ort(K). (1); AFINA ZAHRA CHAIRUNNISA (2); Dr. drg. Ananto Ali Alhasyimi, MD.Sc., Sp.Ort (3)
Tanggal/Date
8 2019
Kata Kunci/Keyword
Abstrak/Abstract
Background: Patients with fixed orthodontic encounter problems in cleaning their teeth and
mouths. Dental plaque tends to accumulate on wires, brackets, and surfaces between bonding
materials and brackets. Plaque accumulation increases the risks of decalcification, caries, and
gingivitis. Chitosan extract is a potential antibacterial agent and inhibitor of dental plaque
formation. This study aims to assess the effectiveness of chitosan-containing dentifrice in
decreasing plaque accumulation in patients with fixed orthodontic appliances.
Materials and Methods: This was a prospective, randomized, double-blind study which involved
32 samples (randomly allocated to the control and chitosan groups, after the power of the study was
considered) from patients with orthodontic appliances undergoing the last stage of fixed active
orthodontic treatment. Plaque accumulation before and after dentifrice use was measured using a
plaque index according to O'leary, before and after using toothpaste within 5 days. The subjects
were instructed to brushing with chitosan-containing dentifrice and chitosan-free dentifrice as a
control. Wash out period that needed between brushing with chitosan-containing dentifrice and
chitosan-free dentifrice as a control was 7 days. Each mouthwash used routinely for 5 days with
same duration and intensity. The data obtained were then analyzed with one-way ANOVA
followed by post-hoc LSD. The level of significance was set to 0.05. Results: Plaque accumulation
before and after dentifrice use significantly differed (P < .05) between the control and chitosan
groups. The average reductions in plaque accumulation was greater in the chitosan group and
control group brushing using chitosan-containing dentifrice. Conclusion: Dentifrice containing
chitosan more effectively reduces dental plaque accumulation in patients with fixed orthodontic
appliances than dentifrice without chitosan.
