Effect of Cinnamomum burmannii Nees ex Bl. and Massoia aromatica Becc. Essential Oils on Planktonic Growth and Biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus In Vitro
Penulis/Author
Dr. Sylvia Utami Tunjung Pratiwi, S.Si., M.Si. (1); Prof. Dr.rer.nat. apt. Triana Hertiani, S.Si., M.Si. (2)
Tanggal/Date
2015
Kata Kunci/Keyword
Abstrak/Abstract
Biofilms are communities of microorganisms that can be found in almost every habitat. They can be attached to a surface and protected by an extracellular matrix of biomolecules that substantially protect microorganisms from environmental effects. The aim of this research is to explore the potency of essential oils from Cinnamomum burmannii Nees ex Bl. and Massoia aromatica Becc. against planktonic growth and biofilm formation of, two opportunistic pathogens, Pseudomonas aeruginosa PAO1 and Staphylococcus aureus Cowan I. Essential oil from C. burmannii and M. aromatica showed a 50% inhibition of P. aeruginosa and S. aureus planktonic growth (PMIC50) at concentration of 0.12 % v/v. Essential oil from C. burmannii and M. aromatica showed capability to inhibit 50% (MBIC50) of P. aeruginosa and S. aureus biofilm formation at concentration of 0.03 % v/v, whereas higher concentration (0.12 % v/v) was needed by C. burmannii and M. aromatica oil to disrupt 50% of P. aeruginosa and S. aureus established biofilm. The analysis by GC-MS showed cinnamic aldehyde (92.02 %) to be the major component of C. burmannii essential oil, whereas Massoialactone (92.05 %) was the main constituent of M. aromatica essential oil. The results obtained in this study have made the oil of C. burmannii and M. aromatica oil as an interesting source for antibiofilm agents in the development of new strategies to treat infections caused by P. aeruginosa and S. aureus biofilm.
Rumpun Ilmu
Biologi Farmasi
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
Effect of C burm Ma against Pa Sa.pdf
2
Effect of Cinnamomum burmannii Nees ex Bl_ and Massoia aromatica Becc_ Essential Oils on Planktonic Growth and Biofilm formation of Pseudomonas aeruginosa and Staphylococcus aureus.pdf