Effect of Cinnamaldehyde, an Anti-Inflammatory Agent, on the Surface Characteristics of a Plaster of Paris – CaCO3 Hydrogel for Bone Substitution in Biomedicine
Penulis/Author
Dr. drg. Anne Handrini Dewi, M.Kes. (1); drg. Heribertus Dedy Kusuma Yulianto, M.Biotech., Ph.D (2); Prof. drg. Ika Dewi Ana, M.Kes., Ph.D. (3); Prof. Ir. Rochmadi, S.U., Ph.D., IPU. (4); Prof. Dr. drg. Widowati Siswomihardjo, M.S. (5)
Tanggal/Date
2020
Kata Kunci/Keyword
Abstrak/Abstract
Combining an anti-inflammatory agent derived from a plant essential oil, such as
cinnamaldehyde, with bioabsorbable and osteoconductive material as a bone substitute is a
challenge in biomedical technology. In this study, cinnamaldehyde, a good anti-inflammatory agent
with an aromatic ?, ?-unsaturated aldehyde derived from cinnamon, was loaded in composites of
plaster of Paris (POP) and calcium carbonate (CaCO3) hydrogel as a bone substitute. However,
during blood–biomaterial interactions, which start after surgical implantation, blood protein
adsorption to the biomaterial surface occurs prior to interaction with host cells. Therefore, before a
device is ready for implantation, the influence of cinnamaldehyde on the property of the composite,
especially its surface characteristics, needs to be examined. The aim of this research was to
investigate the effect of cinnamaldehyde on the surface topography, contact angle, and surface
roughness of a POP–CaCO3 hydrogel scaffold. The results indicate that cinnamaldehyde increased
the contact angle and surface roughness of the POP hydrogel, which seemed to be homogenous on
all surfaces.
Rumpun Ilmu
Ilmu Kedokteran Gigi
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
Full Dokumen - IJTech 2020.pdf
[PAK] Full Dokumen
2
IJTech Appendix.pdf
3
Bukti Korespondensi IJTech 2020.pdf
[PAK] Bukti Korespondensi Penulis
4
Akreditasi International Journal of Technology.pdf
5
Similaritas 2020 -21%-IJTech-R2-CE-4313-Effect of Cinnamaldehyde.pdf
