Karya
Judul/Title Docking of 1-phenylsulfonamide-3-trifluoromethyl-5-parabromophenyl-pyrazole to cyclooxygenase-2 using plant
Penulis/Author Stefanus Laily Prasojo (1); Fajar Agung Dwi Hartanto (2); Dr. apt. Nunung Yuniarti, S.F., M.Si. (3); Prof. Dr. apt. Zullies Ikawati. (4); Enade Perdana Istyastono (5)
Tanggal/Date 28 2010
Kata Kunci/Keyword
Abstrak/Abstract The docking protocols to virtually screen selective cyclooxygenase-2 (COX-2) ligands using PLANTS docking software were developed and validated. The crystal structure of 1-phenylsulfonamide-3-trifluoromethyl-5-parabromophenyl-pyrazole (S58) binds to cyclooxygenase-2 (COX-2) was used as the reference structure. The developed protocols could predict the binding pose of S58 to COX-2 accurately (RMSD is 1.2 ?).
Rumpun Ilmu Farmakologi dan Farmasi Klinik
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
1paper 14 KP Nunung Yuniarti LK 2019.pdf[PAK] Full Dokumen
2Turnitin Docking of 1-phenylsulfonamide-3-trifluoromethyl-5-parabromophenyl-pyrazole to cox-2.pdf[PAK] Cek Similarity
3Sertifikat Akreditasi IJC 2010.pdfDokumen Pendukung Karya Ilmiah (Hibah, Publikasi, Penelitian, Pengabdian)