Karya
Judul/Title Development of a Biobank from a Legacy Collection in Universitas Gadjah Mada, Indonesia: Proposed Approach for Centralized Biobank Development in Low-Resource Institutions
Penulis/Author Jajah Fachiroh, SP., M.Si., Ph.D. (1) ; dr. Ery Kus Dwianingsih, Ph.D., Sp.PA(K) (2); Amirah Ellyza Wahdi (3); Linda Tri Pramatasari (4); Sunandar Hariyanto, S.T., M.Eng. (5); Nenes Prastiwi (6); dr. Junaedy Yunus, M.Sc., Ph.D. (7); Maimuna Mendy (8); Bart Scheerder (9); dr. M. Lutfan Lazuardi, M.Kes., Ph.D. (10)
Tanggal/Date 19 2019
Kata Kunci/Keyword
Abstrak/Abstract Introduction: The establishment of a biobank requires specific expertise along with relatively expensive in- frastructure and appropriate technology. This causes certain challenges in biobank implementation for research in low–middle-income countries. Biobank development with established specimens and data collection (legacy collection) was an approach used in the Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada. This approach aimed to identify the resources available at present, while providing nontechnical in- formation for further development of a centralized biobank. Materials and Methods: Retrospective modeling was done in 2015 by recruiting existing specimen collections and their associated data. The steps were as follows: (1) informing research stakeholders through discussion with experts and stakeholders; (2) identifying specimen collections to be used; (3) determining the system, infrastructure, and consumables needed; (4) determining inclusion criteria; (5) building an in-house database system; (6) organizing data and physical specimen collections; and (7) validating data and physical sample arrangement. All technical procedures were built into standard operating procedures. Results: The model included specimens from one -80C freezer. The associated data included demographic, clinical diagnosis, and physical sample information. Samples came from six studies, collected between 2001 and 2014. A web-based database was built based on the MySQL programming system. Information on bio- specimens from a total of 4196 subjects collected in 11,358 vials was entered into the database, following physical rearrangement of vials in the -80C freezer with one-dimensional barcodes taped to vials, boxes, and racks. A validation test was done for data concordance between the database and physical arrangement in the -80C freezer, showing no discrepancies. Conclusion: This report demonstrated current technical and nontechnical insights to further develop a cen- tralized biobank for health research at an academic institution in Indonesia.
Rumpun Ilmu Ilmu Biomedik
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
1form-L1-permohonan_penghargaan-karya-ilmiah-sudah-terbit-2020_jajahfachiroh.pdf
2Similarity_Development of a Biobank from a Legacy Collection in Universitas Gadjah Mada, Indonesia Proposed Approach for Centralized Biobank Development in Low-Resource Institutions.pdf[PAK] Cek Similarity
3Fulldok_Development of a Biobank from a Legacy Collection in Universitas Gadjah Mada, Indonesia Proposed Approach for Centralized Biobank Development in Low-Resource Institutions.pdf[PAK] Full Dokumen
4bukti korespondensi_2019_bio_fachiroh_biobank-compressed.pdf[PAK] Bukti Korespondensi Penulis