| Judul/Title |
Cytoprotective and antioxidant effects of ethanolic extract of red dragon fruit (Hylocereus polyrhizus) and carrot (Daucus carota L.) |
| Penulis/Author |
NISA ISNENI HANIFA (1); apt. Rumiyati, S.Si., M.Si., Ph.D. (2) ; Prof. Dr. apt. Sismindari, S.U. (3); Prof. Dr.rer.nat. Nanang Fakhrudin, M.Si., Apt. (4) |
| Tanggal/Date |
2016 |
| Kata Kunci/Keyword |
|
| Abstrak/Abstract |
Red dragon fruit (Hylocereus polyrhizus) and carrot (Daucus carota L.) have been known for their phenolic and flavonoid compounds with antioxidants properties. Antioxidant activities including ?-carotene bleaching (BCB) and Cupric ion Reducing Antioxidant Capacity (CUPRAC) and total phenolic content (TPC), total flavonoid content (TFC), and cytoprotective effect of the red dragon fruit and carrot extracts have been investigated in this study. Various concentrations of red dragon fruit (25-150?g/mL) and carrot (25-200?g/mL) extracts were applied on fibroblast primary cell which has been previously treated with 1000 ?M hydrogen peroxide (H2O2) on the cytoprotective test. Results demontrated that carrot extract had higher antioxidant activity, TPC, and TFC than red dragon fruit extract. It was found that red dragon fruit extract at concentration of 150?g/mL and carrot extract at concentration of 200?g/mL were not able to protect cells from H2O2 exposure. © 2016 Author(s). |
| Rumpun Ilmu |
Farmakologi dan Farmasi Klinik |
| Level |
Internasional |
| Status |
|
