Karya
Judul/Title Biochemical Responses and DNA Damage of Chlorella pyrenoidosa H.Chick upon Exposure to Combined Cu and Cd at Environmentally Realistic Levels
Penulis/Author Prof. Dr. rer. nat. Andhika Puspito Nugroho, S.Si., M.Si. (1) ; Prof. Dr. Niken Satuti Nur Handayani, M.Sc. (2); Sari Darmasiwi, S.Si., M.Biotech., Ph.D. (3); WILDAN G. ZULFIKAR (4); Ahmad A. Rizki (5)
Tanggal/Date 29 2020
Kata Kunci/Keyword
Abstrak/Abstract Monitoring aquatic ecosystems is necessary to prevent or reduce the impact of metal pollutants on ecosystems and human health. Biological responses, or biomarkers, can provide quick and direct evidence of exposure to environmental stressors. This study evaluated the sensitivity of biomarkers of Chlorella pyrenoidosa after short-term exposure to combined copper and cadmium at environmentally realistic concentrations with the following biological endpoints: growth; alkaline phosphatase activity; chlorophylls, pheophytin-a, carbohydrate, and protein content; and DNA damage. C. pyrenoidosa was exposed to three combinations of copper and cadmium for 120 min, or for 48 h to assess its DNA damage. To assess the sensitivity of the biological responses to the combined metals, integrated biomarker response (IBR) analysis was also performed. The results demonstrated that exposure to combined Cu and Cd caused an inhibition of growth and activity of alkaline phosphatase, a decrease of chlorophyll-a and -b and protein, and an increase of pheophytin-a and tail factors DNA. The IBR analysis affirmed that the inhibition of alkaline phosphatase activity and the decrease of protein level were responsive biomarkers for exposure to the combined metals.
Rumpun Ilmu Biologi (dan Bioteknologi Umum)
Bahasa Asli/Original Language English
Level Internasional
Status
Dokumen Karya
No Judul Tipe Dokumen Aksi
1ENRJ 18(3) 2020-dikompresi.pdf[PAK] Full Dokumen
2sim 1_Biochemical Responses and DNA Damage of Chlorella pyrenoidosa H_ Chick upon Exposure to Combined Cu and Cd at Environmentally Realistic Levels.pdf[PAK] Cek Similarity
3Bukti Korespondensi Biochemical Responses and DNA Damage of Chlorella pyrenoidosa H_Chick upon Exposure to Combined Cu and Cd at Environmentally Realistic Levels REVISI 1.pdf[PAK] Bukti Korespondensi Penulis
413_ Surat keterangan Biochemical Responses and DNA Damage of Chlorella pyrenoidosa H_Chick upon Exposure to Combined Cu and Cd at Environmentally Realistic Levels (validasi)_docx.pdfDokumen Pendukung Karya Ilmiah (Hibah, Publikasi, Penelitian, Pengabdian)
5Biochemical Responses and DNA.pdf[PAK] Full Dokumen