| Abstrak/Abstract |
In Indonesia, bengkoang roots (Phacyrhizus erosus) have been used as excipient for, sun screening and skin whitening paste. Since the active compounds exhibiting skin whitening or sun screening effect have not been studied previously, the aim of the study was to identify compounds with antioxidant and tyrosinase inhibitor activities. Soxhlet extraction was used as a method of isolation with petroleum ether as solvent and it was followed by fractionation using ethyl acetate to obtaine three isoflavonoids (i.e. daidzein (2); daidzein-7-O-ß-glucopyranose (3); 5-hydroxy-daidzein-7-O-ß-glucopyranose (4)), and a new pterocarpan (i. e. 8,9-furanyl-pterocarpan-3-ol (1)) which antioxidant activities (SC50% values) of 2,11; 11,86; 0,69 and 7,86 respectively. All compounds showed tyrosinase inhibitory activities with IC50 values of 4.38, 5.35, 7.49 and 22.20 mM, respectively for compound 4, 2, 1 and 3. These compounds can be used as antioxidant and skin whitening materials |
