Assessment of Vertical Dengue Virus Transmission in Aedes aegypti and Serotype Prevalence in Bantul, Indonesia
Penulis/Author
Prof. dr. Tri Baskoro Tunggul Satoto, M.Sc., Ph.D. (1); Dr. drh. Sitti Rahmah Umniyati, S.U. (2); Fardhiasih Dwi Astuti (3); Dr.biol.hom. Nastiti Wijayanti, S.Si., M.Si. (4); Laurent Gavotte (5); Christian A. Devaux, Ph.D. (6); Roger Frutos (7)
Tanggal/Date
2014
Kata Kunci/Keyword
Abstrak/Abstract
Abstract
Objective
To determine the reality of dengue virus (DENV) serotype circulation in Bantul and the potential impact of a vertical transmission in the maintenance of dengue.
Methods
Mosquitoes were captured using ovitraps in the vicinity of households of patients diagnosed with severe forms of dengue. DENV was detected in mosquitoes by immunochemistry and typed by reverse transcription-polymerase chain reaction.
Results
Aedes aegypti mosquitoes infected with DENV were found in 14 out of 17 districts in the Bantul Regency. Vertical transmission was demonstrated and serotype prevalence was coherent with the current clinical situation and the previous reports. DENV-3 was the most common serotype (12 districts), followed by DENV-2 (3 districts) and DENV-4 (1 district). No DENV-1 was found.
Conclusions
Unlike continental countries such as Cambodia or Thailand, where the replacement of serotypes is the rule, maintenance of DENV-3 is a major feature in Java. Vertical transmission is likely to play a major role along with the archipelago structure of Indonesia, which might help maintaining local mosquito populations. Regular survey of circulating DENV and prevalence will help predicting and controlling outbreaks.
Rumpun Ilmu
Ilmu Kedokteran Tropis
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
Assesment of vertical Dengue virus transmission on A_ aegypti, 2014.pdf
[PAK] Full Dokumen
2
Assessment of vertical dengue virus transmission in Aedes aegypti and serotype prevalence in Bantul, Indonesia (1).pdf
[PAK] Cek Similarity
3
Assessment of vertical dengue virus transmission in Aedes aegypti.pdf