Antioxidant activity, total phenolic, and total flavaonoid of extracts and fractions of red fruit (Pandanus conoideus Lam)
Penulis/Author
Prof. Dr. Abdul Rohman, S.F., M.Si., Apt. (1); Prof. Dr. apt. Sugeng Riyanto, MS. (2); Dr. apt. Nunung Yuniarti, S.F., M.Si. (3); WAKHID RIZKA SAPUTRA (4); RIKA CAHYANING UTAMI (5); WIDI MULATSIH (6)
Tanggal/Date
2010
Kata Kunci/Keyword
Abstrak/Abstract
Red fruit (Pandanus conoideus Lam) is one of the fruits commonly consumed as diet by societies,
especially in Papua, Indonesia. Preliminary research revealed that among three extracts of red fruit evaluated,
ethyl acetate extract had the highest antiradical activities; therefore, this research was directed to fractionate
ethyl acetate extract, evaluate antioxidant activities using in vitro methods of 2,2-diphenyl-1-picrylhydrazyl
(DPPH) radical scavenging, reducing power, and metal chelating activity, and to determine the phenolics and
flavonoid contents of ethyl acetate extract and its fractions. Ethyl acetate extract and its fractions can strongly
scavenge DPPH radical with IC50 value ranged from 5.25 to 53.47?g/ml. Its antiradical scavenging activity
revealed a moderate relationship with the total phenolics content (r2 = 0.645) and with flavonoid content (r2 =
0.709). Ethyl acetate extract and its fractions also had a capability to reduce Fe3+ to Fe2+ with reduction activity
ranged 91.26 – 682.18 ?g ascorbic acid equivalent/g extract or fraction. These extract and its fractions had
metal chelating activity lower than that of EDTA (IC50 18.19 ?g/ml). Red fruit can be used as natural antioxidant
source to prevent diseases associated with free radical.
Rumpun Ilmu
Farmakologi dan Farmasi Klinik
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
paper 1 KP Nunung Yuniarti LK 2020.pdf
[PAK] Full Dokumen
2
Antioxidant activity, total phenolic, and total flavaonoid of extracts and fractions of red fruit (Pandanus conoideus Lam).pdf
