Antihyperglicemic Activity of Some Chromium (III)-amino acid Complexes inNicotinamide-Strepzotocine Induced Diabetic Wistar
Penulis/Author
KUN SRI BUDIASIH (1); Prof. Dr. Chairil Anwar (2); Dr. Hilda Ismail, M.Si., Apt. (3); Prof. Drs. Sri Juari Santosa, M.Eng., Ph.D. (4); Prof. Dr. Ika Puspita Sari, S.Si., M.Si., Apt. (5)
Tanggal/Date
2013
Kata Kunci/Keyword
Abstrak/Abstract
Investigation of an in vivo application of chromium- amino acid complexes was conducted on nicotinamidestreptozotocin
induced diabetic Wistar rats. The rats were divided into 9 groups each consist of 4 animals. Three
groups are control (+) with chromium picolinate (CrPic), control (-)diabetic group (DM) and control non diabetic
(non DM). Furthermore, three groups wereexamined on the effect of Formula A (Cr-glutamate by 1:3 ratio)at dose
(100, 200 and 400 ?g/day). In addition, the last 3 groups were studied on the effect of different formula of Cr (III)-
glutamato made of Cr-glutamate by ratio 1:2 (200 ?g/day), Cr-glycine (1:3) and Cr-cysteine(1:3) complexes. The
blood glucose levels were measured before and after treatment. All formulas gave significant effect in lowering
glucose level (p 0.05) compared to diabetic rats control group.
Rumpun Ilmu
Analisis Farmasi dan Kimia Medisinal
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
10_Antihyperglicemic activity of some chromium(III)-amino acid complexes in nicotinamide-streptozotocin induced diabetic wistar rats.pdf
