| Penulis/Author |
DARU ESTININGSIH (1); Prof. Dr. Ika Puspita Sari, S.Si., M.Si., Apt. (2) ; Prof. dr. Titik Nuryastuti, M.Si., Ph.D., Sp.MK(K). (3); Prof. Dr.rer.nat. apt. Raden Rara Endang Lukitaningsih, S.Si., M.Si. (4) |
| Abstrak/Abstract |
Background: The use of antibiotics is one of the procedures in the treatment of infectious
diseases. Antibiotic are given to kill or inhibit the growth of infectious bacteria within the
host’s system. Inappropriate use of antibiotics may lead to antibiotic resistance where
the bacteria able to resist the effect of the drugs. Objective: The purpose of this study
was to determine the pattern of antibiotic use and antibiotic resistance in out-patients at
the Pakem Health Center, Yogyakarta. Method: This study employed a descriptive
research design using the data of patients with bacterial infections. Twenty-six patients
were the subjects of the study with predetermined characteristics, namely age, gender,
occupation, and antibiotics given. Result: The result showed the five (5) common types
of infections were pyoderma, pharyngitis, abscess, bronchitis, and wound infection.
Meanwhile, the infectious bacteria found were Staphylococcus aureus, Streptococcus
pyogenes, Klebsiela pneumoniae, Acinetobacter baumannii, Klebsiella oxytoca,
Pseudomonas aeruginosa, and Streptococcus betahaemolyticus. The prescribed
antibiotics included amoxicilin (73.33%), metronidazole (16.67%), gentamicin (6.67%),
and ciprofloxacin (3.33%). The antibiotic resistant bacteria were Acinetobacter
baumannii, Klebsiela pneumoniae, Klebsiella oxytoca, and Staphylococcus aureus. Among
the test bacteria, several groups showed multiple-drug resistance. The five highest
antibiotic resistance found were penicillin (52.9%), ampicillin (40.0%), tetracycline
(33.3%), cefuroxime (33.3%), and amikacin (33.3%). Conclusion: The most common
type of infection was pyoderma and the antibiotic treatment given to most occurring
cases of infection was amoxicillin. |
