| Penulis/Author |
DARU ESTININGSIH (1); Prof. Dr. Ika Puspita Sari, S.Si., M.Si., Apt. (2) ; Prof. dr. Titik Nuryastuti, M.Si., Ph.D., Sp.MK(K). (3); Prof. Dr.rer.nat. apt. Raden Rara Endang Lukitaningsih, S.Si., M.Si. (4) |
| Abstrak/Abstract |
Background: The incidence and development of antibiotic resistance have been shown to have an impact on the ineffectiveness of therapy and are associated with the increased morbidity and mortality, length of hospitalization, and cost of treatment. Antibiotic-resistant bacteria can spread among bacteria, from treated patients to others, or through the environment. Therefore, mapping the profile of antibiotic resistance in health care facilities such as hospitals, health centers and the surrounding environment becomes crucial. Objective: To determine the profile of antibiotic use, antibiotic resistance and infection-causing bacteria in the community setting. Method: This was a descriptive-analytical observational study with cohort design in patients with respiratory infections, acute gastroenteritis, or skin infection/ulcer at Turi Primary Health Care, Yogyakarta. Result: The infection-causing bacteria were Staphylococcus aureus (36%), Streptococcus pyogenes (16%), Streptococcus beta hemolyticus (12%), Klebsiella pneumonia (10%), Escherichia coli (6.05%), and other bacteria in amounts less than 5%. The three largest types of infections occured were respiratory infections (20%), ulcus (18%), pharyngitis, and pyoderma (12.2%). Antibiotics used in infection therapy were amoxicillin 57%, ciprofloxacin 40%, and doxiciclin 2%. Antibiotic sensitivity test results obtained amoxicillin resistance 54%, tetracycline 50%, amoxiclav 33%, chloramphenicol 20%, and the rest were less than 10%. Conclusion: In this study, bacteria were resistant to 9 types of antibiotics, two of which were amoxicillin and tetracycline with a resistance percentage of more than 50%. While the majority of infection-causing bacteria was Staphylococcus aureus which was resistant to 6 types of antibiotics, namely penicillin, tetracycline, chloramphenicol, gentamycin, erythromycin and cefazolin.
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