Vibriosis cause problem in aquaculture and human health. The antibiotic resistance and the limited availability of antimicrobial agents are driving force for searching new antivibrio compounds from natural products. Herein, we evaluated ten marine Actinobacteria isolated from red seaweed Gelidiella acerosa for antivibriosis, cytotoxicity, and secondary metabolites genes in the way to find a new antivibrio agent. Five Actinobacteria isolates exhibited activity against Vibrio alginolyticus and Vibrio parahaemolyticus with MIC ranging from 0.625 - 5 μg/μL. All isolates displayed no cytotoxicity against Vero cell line except for isolate DR-2R-115-8. All isolates harbor nrps gene which might indicate that these isolates have great potential in production of bioactive peptides while none of isolates showed the presence of pks I, II, and hmgcr genes. Identification of ten isolates marine Actinobacteria associated with red algae were classified into four genera of Brevibacterium, Nocardiopsis, Allokutzneria, and Brachybacterium. Our study revealed that the marine Actinobacteria associated with red algae Gelidiella acerosa were promising sources for controlling vibriosis.
Rumpun Ilmu
Bioteknologi Perikanan
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
cek similarity - Antivibriosis and cytotoxicity of Actinobacteria associated with ___.pdf
[PAK] Cek Similarity
2
AquaResearch-Correspondence.pdf
[PAK] Bukti Korespondensi Penulis
3
artikel - Antivibriosis and cytotoxicity of Actinobacteria associated with red seaweed Gelidiella acerosa.pdf
Bukti Published
4
2021_Ulfah_SuKet_Publikasi_Nastiti Wijayanti.pdf
Dokumen Pendukung Karya Ilmiah (Hibah, Publikasi, Penelitian, Pengabdian)
