Alteration of mucosa cell maturation pattern after exposure to different radiography imaging methods
Penulis/Author
drg. Ryna Dwi Yanuaryska, Ph.D (1); SABRINA CEASY ANGGRAENI (2); Adhara Harvita Puspitasari (3); Dr. drg. Rurie Ratna Shantiningsih, MDSc. (4); Prof. Dr. drg. Munakhir Mudjosemedi, S.U., Sp.RKG(K). (5); drg. Rellyca Sola Gracea, Sp.R.K.G. (6)
Tanggal/Date
21 2021
Kata Kunci/Keyword
Abstrak/Abstract
Aim: Dental imaging has been widely used for diagnosis in
dentistry. However, dental X-ray may induce cytotoxicity leading to
apoptosis in oral mucosa cells. The present study aimed to observe
the maturation pattern of buccal and gingival cells after exposure
to X-ray radiation from analog/digital panoramic scanning and
cone beam computed tomography (CBCT). Methods: The
research samples were 40 subjects who fulfilled the inclusion
and exclusion criteria. The subjects were divided into the exposed
(patients who received analog/digital panoramic radiography
or CBCT) and controlled (patients who had no radiography
examinations) groups, with 10 subjects in each group. Exfoliative
cytology smears were obtained from buccal mucosa and gingiva
before exposure (or on day 0 for the control group) and 10 days
later. The cells were stained with the Papanicolaou method. Then,
the superficial, intermediate, and parabasal cells were counted
in each glass slide. Results: No significant differences (p > 0.05)
were observed among all cell types between day 0 and 10 in
the control group. Meanwhile, after exposure to three kinds of
radiography examinations, the frequency of intermediate cells
in buccal mucosa and gingiva increased (p < 0> 0.05). The
frequency differences between intermediate and superficial cells
showed no significant difference between the buccal mucosa and
gingiva. Conclusion: Analog/digital panoramic radiography and
CBCT exposure can induce cytotoxicity by altering the maturation
pattern of buccal mucosa cells and gingiva, so it is strongly
recommended to only perform these procedures if necessary and
avoid repeated exposure to the same patient.
Rumpun Ilmu
Bidang Spesialis Kedokteran Gigi Lain Yang Belum Tercantum
Bahasa Asli/Original Language
English
Level
Internasional
Status
Dokumen Karya
No
Judul
Tipe Dokumen
Aksi
1
BJOS 2021_RYNA DWI Y.pdf
[PAK] Full Dokumen
2
Bukti korespondensi_komplit.pdf
[PAK] Bukti Korespondensi Penulis
3
Surat Keterangan Publikasi Mhs_Alteration of mucosa cell maturation pattern.pdf
Dokumen Pendukung Karya Ilmiah (Hibah, Publikasi, Penelitian, Pengabdian)