A synthesis of polyethylene glycol (PEG)-coated magnetite Fe3O4 nanoparticles and their characteristics for enhancement of biosensor
Penulis/Author
Ganesha Antarnusa (1); Prof. Dr.Eng. Edi Suharyadi, S.Si., M.Eng. (2)
Tanggal/Date
2020
Kata Kunci/Keyword
Abstrak/Abstract
The magnetite Fe3O4nanoparticles were synthesized by using chemical co-precipitation method and these
nanoparticles were successfully coated by polyethylene glycol(PEG)with variation concentrations of PEG.
The magnetite Fe3O4nanoparticles used as a bimolecular label(nano-tags), exhibiting a soft magnetic
behavior with magnetization (Ms) of 77.16 emu g?1 and coercivity (Hc) of 50 Oe respectively. The
polyethylene glycol(PEG)was used as a biocompatible polymer. The x-ray diffraction(XRD) patterns of
the Fe3O4 showed that Fe3O4was well crystallized. It also confirmed the existence of invers spinel. The
diffraction peak of 35.4°was used to calculate the crystallite size. The estimation of Fe3O4 average crystallite
size is 12 nm, while the PEG-coated Fe3O4nanoparticles is 8.6 nm. The transmission electron microscopy
(TEM)images of Fe3O4 showed that the morphology of magnetite Fe3O4nanoparticle is spherical in shape
with uniform grain size and good dispersibility despite the agglomeration itfound in some place. The
addition of PEG can decrease the agglomeration and reduce the particle size. The existence of PEG layer on
Fe3O4was confirmed by Fourier transform infrared (FTIR)spectroscopy. The result of Vibrating Sample
Magnetometer(VSM)showed that saturation magnetization (Ms) of Fe3O4nanoparticles decreasedfrom
77.16 to 37.15 emu g?1 with the increase of PEG weightfrom 0% to 50%. Such Fe3O4nanoparticles with
favorable size and tunable magnetic properties are promising biosensor applications.
